houseofmind:

 
A novel method of gaining a clear view of the brain (literally) emerges 
(Clicking on the image links back to the original article featured in the NY Times). 
Japanese neuroscientists at the Riken Brain Institute may have found a way to visualize the brain’s gray matter, which consists of a neuronal cell bodies, neuropil, glia and such. They have created a chemical concoction, termed Scale, that makes dead and opaque (biological) tissue into a clear and jelly-like substance. Thus, soaking brains into this special solution enables scientists to preserve and physically observe what’s inside the brain. The development of this new chemical approach towards visualizing the brain may be revolutionary in the study of the brain’s neural architecture and connectivity as well as neural development. 
Click here for the link to the original article published in Nature Neuroscience.  I highly recommend you check out the original article- the images are just too cool!
Oh, and I forgot to mention: there’s already talk of international collaborations that would apply this method to study HUMAN brains. What what?!

houseofmind:

A novel method of gaining a clear view of the brain (literally) emerges

(Clicking on the image links back to the original article featured in the NY Times). 

Japanese neuroscientists at the Riken Brain Institute may have found a way to visualize the brain’s gray matter, which consists of a neuronal cell bodies, neuropil, glia and such. They have created a chemical concoction, termed Scale, that makes dead and opaque (biological) tissue into a clear and jelly-like substance. Thus, soaking brains into this special solution enables scientists to preserve and physically observe what’s inside the brain. The development of this new chemical approach towards visualizing the brain may be revolutionary in the study of the brain’s neural architecture and connectivity as well as neural development. 

Click here for the link to the original article published in Nature Neuroscience.  I highly recommend you check out the original article- the images are just too cool!

Oh, and I forgot to mention: there’s already talk of international collaborations that would apply this method to study HUMAN brains. What what?!

psydoctor8:

Neurophysicists to everyone: “There is an optimal brain frequency”
We may be familiar with the concept of electrical/chemical signals relating to neural communication. So, now imagine of every synapse branching out from every neuron - like an antenna, is tuned to a different frequency signal with a specific optimal point and this optimum frequency point depends on the location of the synapse on a neuron. The farther away the synapse is from the neuron’s cell body, the higher the optimum frequency was found to be.  And it seems the more rhythmicly synced the frequencies were - the stronger the connection for memory and learning synapses.

 The researchers found that not only does each synapse have a preferred frequency for achieving optimal learning, but for the best effect, the frequency needs to be perfectly rhythmic — timed at exact intervals. Even at the optimal frequency, if the rhythm was thrown off, synaptic learning was substantially diminished.

 

Their research also showed that once a synapse learns, its optimal frequency changes. In other words, if the optimal frequency for a naïve synapse — one that has not learned anything yet — was, say, 30 spikes per second, after learning, that very same synapse would learn optimally at a lower frequency, say 24 spikes per second. Thus, learning itself changes the optimal frequency for a synapse.

As well as possibly strengthening and enhancing learning and memory, learning-induced re-tuning and de-tuning could be have “important implications for treating disorders related to forgetting, such as PTSD disorder”.  via

Life is just a frequency…

The image shows a neuron with a tree trunk-like dendrite. Each triangular shape touching the dendrite represents a synapse, where inputs from other neurons, called spikes, arrive (the squiggly shapes). Synapses that are further away on the dendritic tree from the cell body require a higher spike frequency (spikes that come closer together in time) and spikes that arrive with perfect timing to generate maximal learning. VIA

image

psydoctor8:

Neurophysicists to everyone: “There is an optimal brain frequency”

We may be familiar with the concept of electrical/chemical signals relating to neural communication. So, now imagine of every synapse branching out from every neuron - like an antenna, is tuned to a different frequency signal with a specific optimal point and this optimum frequency point depends on the location of the synapse on a neuron. The farther away the synapse is from the neuron’s cell body, the higher the optimum frequency was found to be.  And it seems the more rhythmicly synced the frequencies were - the stronger the connection for memory and learning synapses.

 The researchers found that not only does each synapse have a preferred frequency for achieving optimal learning, but for the best effect, the frequency needs to be perfectly rhythmic — timed at exact intervals. Even at the optimal frequency, if the rhythm was thrown off, synaptic learning was substantially diminished.

Their research also showed that once a synapse learns, its optimal frequency changes. In other words, if the optimal frequency for a naïve synapse — one that has not learned anything yet — was, say, 30 spikes per second, after learning, that very same synapse would learn optimally at a lower frequency, say 24 spikes per second. Thus, learning itself changes the optimal frequency for a synapse.

As well as possibly strengthening and enhancing learning and memory, learning-induced re-tuning and de-tuning could be have “important implications for treating disorders related to forgetting, such as PTSD disorder”.  via

Life is just a frequency…

The image shows a neuron with a tree trunk-like dendrite. Each triangular shape touching the dendrite represents a synapse, where inputs from other neurons, called spikes, arrive (the squiggly shapes). Synapses that are further away on the dendritic tree from the cell body require a higher spike frequency (spikes that come closer together in time) and spikes that arrive with perfect timing to generate maximal learning. VIA

image